Table 2.

Univariate analysis of LDL-C level and covariates associated with all-cause mortality in the NHANES Study, 1999–2014.

Characteristics	Events/numbers	HR (95% CI)	P
LDL-C (mg/dL)
< 70	161/1557	1.521 (1.276–1.812)	< 0.001
70–99	398/5246	0.992 (0.870–1.132)	0.908
100–129	504/6212	1 (ref)
130–159	352/3996	0.993 (0.861–1.145)	0.925
≥ 160	204/2023	1.218 (1.047–1.416)	0.011
Sex
Men	883/9045	1 (ref)
Women	736/9989	0.725 (0.658–0.800)	< 0.001
Race
Non-Hispanic White	964/8656	1 (ref)
Non-Hispanic Black	260/3872	0.624 (0.544–0.716)	< 0.001
Mexican American	292/3674	0.602 (0.528–0.686)	< 0.001
Other Hispanic	62/1454	0.513 (0.397–0.664)	< 0.001
Other Race	41/1378	0.463 (0.339–0.633)	< 0.001
Marital status
Single	126/4414	1 (ref)
Married	854/10,228	2.834 (2.351–3.417)	< 0.001
Separated/divorced/widowed	605/3643	6.667 (5.502–8.079)	< 0.001
Education level
Primary school	388/2156	1 (ref)
Junior high school	276/2710	0.589 (0.505–0.687)	< 0.001
Senior high school	384/3993	0.566 (0.491–0.652)	< 0.001
College and above	543/8639	0.393 (0.345–0.448)	< 0.001
Smoking status
Never smoker	663/9623	1 (ref)
Former smoker	598/4345	1.941 (1.738–2.168)	< 0.001
Current smoker	290/3157	1.250 (1.089–1.436)	0.002
Hypertension
No	770/13,015	1 (ref)
Yes	846/5924	2.953 (2.678–3.257)	< 0.001
Diabetes
No	1286/17,139	1 (ref)
Yes	330/1889	2.976 (2.636–3.360)	< 0.001
Cardiovascular Disease
No	1215/16,129	1 (ref)
Yes	366/1338	4.436 (3.945–4.987)	< 0.001
Cancer
No	1287/16,027	1 (ref)
Yes	309/1484	3.128 (2.762–3.543)	< 0.001

CIs Confidence intervals, HR hazard ratio, LDL-C low-density lipoprotein cholesterol.