Table 2.

Pearson linear correlation coefficient and p value from Mantel’s test obtained from paired comparisons of pathway analysis results. Pathway analyses were obtained comparing APAP or VPA versus CA in each batch. Correlation was performed comparing pathway analysis results from the same (APAP or VPA; left side) or different (APAP vs VPA; right side) treatments. One asterisk indicates p value < 0.05, two asterisks indicates p value < 0.01.

Comparison	Corr. coef	p val	Sig	Comparison	Corr. coef	p val	Sig
B1vsB2_APAP	0.12	0.109		B1_APAPvsB1_VPA	0.04	0.769
B1vsB3_APAP	0.20	0.035	*	B2_APAPvsB2_VPA	0.24	0.023	*
B1vsB4_APAP	− 0.06	1.001		B3_APAPvsB3_VPA	− 0.05	1.001
B1vsB5_APAP	0.16	0.035	*	B4_APAPvsB4_VPA	− 0.09	1.001
B2vsB3_APAP	0.22	0.014	*	B5_APAPvsB5_VPA	0.03	0.772
B2vsB4_APAP	0.08	0.263		B1_APAPvsB2_VPA	0.03	0.808
B2vsB5_APAP	0.58	0.001	**	B1_APAPvsB3_VPA	− 0.04	1.001
B3vsB4_APAP	0.50	0.001	**	B1_APAPvsB4_VPA	0.05	0.594
B3vsB5_APAP	0.41	0.001	**	B1_APAPvsB5_VPA	− 0.09	1.001
B4vsB5_APAP	0.11	0.110		B2_APAPvsB3_VPA	− 0.03	1.001
B1vsB2_VPA	0.49	0.009	*	B2_APAPvsB4_VPA	0.28	0.019	*
B1vsB3_VPA	0.78	0.001	**	B2_APAPvsB5_VPA	0.24	0.028	*
B1vsB4_VPA	0.41	0.028	*	B3_APAPvsB4_VPA	− 0.10	1.001
B1vsB5_VPA	0.59	0.002	*	B3_APAPvsB5_VPA	− 0.08	1.001
B2vsB3_VPA	0.39	0.012	*	B4_APAPvsB5_VPA	− 0.07	1.001
B2vsB4_VPA	0.88	0.001	**	B2_APAPvsB1_VPA	− 0.04	1.001
B2vsB5_VPA	0.84	0.001	**	B3_APAPvsB1_VPA	− 0.05	1.001
B3vsB4_VPA	0.23	0.076		B3_APAPvsB2_VPA	− 0.12	1.001
B3vsB5_VPA	0.42	0.005	*	B4_APAPvsB1_VPA	− 0.09	1.001
B4vsB5_VPA	0.84	0.001	**	B4_APAPvsB2_VPA	− 0.11	1.001
				B4_APAPvsB3_VPA	− 0.07	1.001
				B5_APAPvsB1_VPA	− 0.00	1.001
				B5_APAPvsB2_VPA	− 0.06	1.001
				B5_APAPvsB3_VPA	− 0.01	1.001
				B5_APAPvsB4_VPA	− 0.02	1.001