Select proteins detected in serum from patients with delirium compared to age- and sex-matched control patients. (A) FGF-21, FGF-23, IL-6, MCP-3, CCL19, and CCL20 expression in control and delirium cohorts at preoperative day 0 and postoperative day (POD) 1; (B) The individual patient response of FGF-21, FGF-23, IL-6, MCP-3, CCL19, and CCL20 from preoperative day 0 to POD1. *p<0.05, **p<0.01, ***p<0.001, and ****p<0.0001 based on an ordinary two-way ANOVA with Šídák’s multiple comparisons test.