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. 2021 Jun 6;10(2):1189–1202. doi: 10.1007/s40122-021-00268-7
Multicenter, randomized, double-blinded crossover study.
Homogenous patient group: chronic, unilateral, neuropathic leg pain after back surgery.
Comparison of 1000 Hz and 30 Hz in the 30-day trial period.
There were no significant differences in the treatment effects of 1000 Hz and 30 Hz at the end of the trial period.
A majority of the patients (16/27) preferred sub-perception threshold stimulation but this was not based on their pain suppression.
Ninety-two percent of patients experienced a minimally important clinical difference (greater than 34% pain suppression).
Fifty percent of patients experienced greater than 80% pain suppression at 1 year.
Quality of life according to patient-reported outcome measures improved at 1 month and were sustained through 1 year.