Table 3.
Summary table of the immune functions of choroidal cell types.
Cell | Immune function | References |
---|---|---|
Cells of haematopoietic origin | ||
Dendritic cell (cDC subtype) | Antigen presentation | (27, 94, 95) |
Tissue macrophage | Cytokine production and antigen presentation | (10, 25, 93, 96, 97) |
Mast cell | Sentinel function, immediate response to pathogens Cytokine production | (29–31, 98, 99, 101) |
Parenchymal and stromal cells | ||
Melanocyte | Response to PAMPs | (42, 108) |
Response to TNFα and IFNγ | (44, 109) | |
Inhibition of T-cell proliferation | (109) | |
Vascular endothelium | Response to PAMPs | (84, 106) |