It is estimated that 20% of the 34 million patients in the United States with diabetes will develop diabetic peripheral neuropathy (PDN).

Treatment has traditionally consisted of medication management, lifestyle modifications, and physical therapy modalities.

There is a growing body of evidence suggesting that spinal cord stimulation is a safe and effective treatment option for patients with diabetic peripheral neuropathy.

Although it is difficult to recommend specific selection criteria based on the literature, PDN patients treated with SCS seem to be older than 50, have diabetic-related pain greater than 5 years, have failed multiple neuropathic medications, and have an A1C less than 10.

Further high-quality studies are warranted to evaluate efficacy as well as clinical guidance regarding patient selection.