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. 2021 Sep 12;10(2):1511–1522. doi: 10.1007/s40122-021-00303-7

Table 1.

Bivariate and multivariate analysis of clinical characteristics

Characteristic Univariate analysis Multivariate analysis
Patients, n (%) OR (95% CI) p value OR (95% CI) p value
MSP MRP
Age
 50–59 28 (56.00) 22 (44.00)
 60–69 32 (35.56) 58 (64.44) 2.29 (1.13–4.70) 0.0212 1.75 (0.68–4.61) 0.2470
 ≥ 70 21 (28.77) 52 (71.23) 3.11 (1.47–6.74) 0.0029 0.69 (0.21–2.13) 0.5246
Gender
 Female 49 (44.55) 61 (55.45)
 Male 32 (31.07) 71 (68.93) 1.78 (1.01–3.14) 0.0445 1.56 (0.66–3.74) 0.3102
Lesion
 Mild 42 (52.50) 38 (47.50)
 Moderate 20 (39.22) 31 (60.78) 1.70 (0.84–3.53) 0.1434 1.33 (0.45–3.88) 0.6012
 Severe 19 (23.17) 63 (76.83) 3.62 (1.86–7.26) 0.0001 3.84 (1.44–10.81) 0.0084
High blood pressure
 No 52 (34.43) 99 (65.56)
 Yes 29 (46.77) 33 (53.23) 0.60 (0.33–1.10) 0.0972 0.36 (0.14–0.87) 0.0266
Diabetes
 No 73 (39.67) 111 (60.33)
 Yes 8 (27.59) 21 (72.41) 1.70 (0.74–4.33) 0.2195
CHD
 No 73 (37.82) 120 (62.18)
 Yes 8 (39.60) 12 (60.40) 0.91 (0.35–2.45) 0.8423
Cancers
 No 78 (38.24) 126 (61.76) 0.83 (0.16–3.34) 1.0000
 Yes 3 (33.33) 6 (66.67×)
Prior antiviral drugs
 No 41 (36.61) 71 (63.39)
 Yes 40 (40.00) 61 (60.00) 0.88 (0.50–1.54) 0.8812
Family history
 Yes 72 (37.11) 122 (62.89)
 No 9 (47.37) 10 (52.63) 0.66 (0.25–1.75) 0.3918
Location
 V1–3 6 (20.00) 24 (80.00)
 C1–8 17 (44.74) 21 (5.26) 0.32 (0.10–0.93) 0.0360 0.28 (0.06–1.12) 0.0783
 T1–12 42 (37.17) 71 (62.83) 0.43 (0.15–1.09) 0.0775 0.53 (0.15–1.74) 0.3083
 C1–T12 9 (52.94) 8 (47.06) 0.23 (0.06–0.85) 0.0276 0.43 (0.07–2.34) 0.3346
 L1–5 3 (75.00) 1 (25.00) 0.10 (0.00–1.01) 0.0478 0.42 (0.02–6.22) 0.5359
 S1–5 1 (33.33) 2 (66.67) 0.49 (0.03–17.11) 0.5235 0.46 (0.01–25.21) 0.7015
 L1–S5 3 (37.50) 5 (62.50) 0.42 (0.07–2.71) 0.3631 0.60 (0.04–10.03) 0.7104
Phase
 AHZ 70 (57.85) 51 (42.15)
 SHZ 10 (18.18) 45 (81.82) 6.05 (2.87–13.85) < 0.0001 8.95 (3.15–29.48) 0.0001
 PHN 1 (2.70) 36 (97.30) 42.74 (8.84–1026.39) < 0.0001 2.37e8 (6.57e−9–1.45e160) 0.9845
 VAS 0.95 (0.78–1.16) 0.5990
 McGill 1.05 (1.01–1.10) 0.0328
 PSQI 1.07 (1.00–1.14) 0.0369
 PHQ9 1.09 (1.03–1.16) 0.0023 1.10 (1.00–1.20) 0.0447
 Anxiety 1.01 (0.99–1.03) 0.2130