Table 2.
Surgical outcomes
| Outcome variables | vNOTES (n = 13) | LESS (n = 13) | P value |
|---|---|---|---|
| Operation time, mins (range) | 55 (25–105) | 75 (50–110) | 0.027 |
| Estimated blood loss, mL (range) | 100 (0–650) | 100 (0–300) | 0.687 |
| Transfusion, n (range) | 0 (0–3) | 0 (0–0) | 0.511 |
| Preoperative hemoglobin, g/dL (range) | 13.1 (9–14.4) | 12.3 (11.114.1) | 0.448 |
| Postoperative hemoglobin, g/dL (range) | 11.6 (7.8–13.8) | 10.8 (8.6–14.0) | 0.920 |
| Hospitalization, days (range) | 4 (4–4) | 4 (4–5) | 0.762 |
| Operation type, n (%) | |||
| Hysterectomy | 1 (7.7%) | 2 (15.4%) | 0.721 |
| Hysterectomy + unilateral salpingo-oophorectomy | 1 (7.7%) | 0 | |
| Hysterectomy + bilateral salpingo-oophorectomy | 6 (46.2%) | 6 (46.2%) | |
| Hysterectomy + bilateral salpingectomy | 5 (38.5%) | 5 (38.5%) | |
| Diagnosis, n (%) | |||
| Myoma | 7 (53.8%) | 7 (53.8%) | 0.544 |
| CIN3 | 3 (23.1%) | 1 (7.7%) | |
| Endometrial hyperplasia | 1 (7.7%) | 1 (7.7%) | |
| Adenomyosis | 1 (7.7%) | 1 (7.7%) | |
| AIS | 0 | 1 (7.7%) | |
| Endometrial cancer | 0 | 2 (15.4%) | |
| Cervical cancer | 1 (7.7%) | 0 | |
| Size of the uterus, cm, (range) | 9.5 (5.1–17) | 9.5 (7–15) | 0.7 |
| Weight of the uterus, g, (range) | 238 (40.8–940) | 196 (93–346) | 0.98 |
| Postoperative complication, n (%) | 0.593 | ||
| Bleeding | 1 (7.7%) | 1 (7.7%) | |
| Surgical site infection | 1 (7.7%) | 0 | |
| Vaginal laceration or suture, n (%) | 4 (30.8%) | 3 (23.1%) | 0.658 |
| Number of additional analgesics, median (range) | 1 (0–3) | 1 (0–3) | 0.647 |
vNOTES vaginal natural orifice transluminal endoscopic surgery, LESS laparo-endoscopic single-site, CIN cervical intraepithelial neoplasia, AIS adenocarcinoma in situ