| Chronic pain is one of the most troublesome sequelae of stroke. It is reported that about 11–55% of stroke patients will suffer chronic pain. |
| Pain after stroke is related to the activation of microglia; there is an urgent need to understand the associated pathophysiological mechanism. |
| This paper reviews studies of the molecular mechanisms of hemorrhagic stroke (HS), especially the activation of microglia and the relationship between microglia and pain after stroke. |
| Microglia are a therapeutic target for hemorrhagic stroke and HS-related pain. |
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