| Why carry out this study? |
| Central poststroke pain (CPSP) typically develops within 1 to 6 months after a stroke, and seriously impairs the patient’s quality of life, mood, and social functioning. |
| Current pharmacological approaches for the treatment of CPSP have failed to provide adequate pain relief. |
| We aimed to evaluate the analgesic effects of repetitive transcranial magnetic stimulation (rTMS) in patients with acute CPSP. |
| What was learned from the study? |
| High-frequency (10 Hz) rTMS applied over the upper extremity area of the motor cortex can effectively alleviate acute CPSP. |
| rTMS may also relieve depression and anxiety after CPSP. |
| The analgesic effects of rTMS may be associated with enhanced cortical excitability and increased secretion of brain-derived neurotrophic factor. |
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