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. 2021 Nov 11;11:22063. doi: 10.1038/s41598-021-01663-y

Table 1.

Baseline characteristics of the citations included for analysis.

Studies (Year)[Reference number] Mean age(years)-GLP1-RA group Sex (Male/Female)-GLP1-RA group Total patients (GLP1-RA/control) Control arm GLP1-RA arm Follow up duration
D-LIFT (2020)9 46.6 ± 9.1 23/9 32/32 Standard of care without GLP1-RA Dulaglutide 0.75 mg/week for 4 weeks, then 1.5 mg/week for 20 weeks 24 weeks
Shao et al. (2014)10 43 ± 4.1 15/15 30/30 Intensive insulin therapy Exenatide 5 µg BID for 4 weeks, then 10 µg BID for 8 weeks 12 weeks
Liu et al. (2019)11 47.63 ± 10.14 19/16 35/36 Glargine Exenatide 5 µg BID for 4 weeks, then 10 µg BID for 20 weeks 24 weeks
Dutour et al. (2016)12 51 ± 2 13/9 22/22 Standard of care without GLP1-RA Exenatide 5 µg BID for 4 weeks, then 10 µg BID for 22 weeks 26 weeks
LEAN (2016)5 50 18/8 26/26 Placebo Liraglutide 1.8 mg 48 weeks
Tang et al. (2015)13 60.7 ± 16.1 11/7 18/17 Glargine Liraglutide 1.8 mg 12 weeks
Tian et al. (2018)14 58.5 +  − 7.6 31/21 52/75 Metformin 1 − 1.5 g/day Liraglutide 0.6—1.8 mg 12 weeks
Newsome et al. (2020)7 54.3 ± 10.2 47/35 82/80 Placebo Semaglutide 0.4 mg/d 72 weeks