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. 2021 Nov 11;11:22063. doi: 10.1038/s41598-021-01663-y

Table 4.

Effect of GLP1-RA versus control on metabolic parameters: (a) Weight, (b) HBA1c, and (c) TG.

Study name Subgroup within study Std diff in means 95% CI p-value Relative weightage (%)
DLIFT Weight − 0.66 − 1.16 to − 0.15 0.01 18.28
Liu et al Weight − 0.98 − 1.47 to − 0.48  < 0.01 19.08
Shao et al Weight − 0.90 − 1.42 to − 0.36  < 0.01 16.42
Tang et al Weight − 0.76 − 1.45 to − 0.08 0.02 9.81
Tian et al Weight − 0.36 − 0.72 to − 0.01 0.04 36.41
Combined effect size Weight − 0.66 − 0.88 to − 0.44  < 0.01 Heterogeneity (I2): 22.35
DLIFT HBA1c − 0.27 − 0.76 to 0.22 0.28 18.46
Liu et al HBA1c − 0.86 − 1.34 to − 0.36  < 0.01 18.94
Shao et al HBA1c − 0.50 − 1.01 to 0.02 0.06 16.95
Tang et al HBA1c − 0.22 − 0.88 to 0.44 0.52 10.12
Tian et al HBA1c − 0.24 − 0.58 to 0.12 0.20 35.53
Combined effect size HBA1c − 0.40 − 0.61 to − 0.19  < 0.01 Heterogeneity (I2): 17.91
DLIFT TG − 0.30 − 0.79 to 0.19 0.23 16.12
Dutour et al TG − 0.36 − 0.96 to 0.22 0.22 11.02
Liu et al TG − 0.12 − 0.59 to 0.34 0.58 18.04
Shao et al TG − 0.50 − 1.01 to 0.02 0.06 14.83
Tang et al TG − 0.43 − 1.10 to 0.24 0.20 8.70
Tian et al TG − 0.02 − 0.37 to 0.33 0.91 31.28
Combined effect size TG − 0.22 − 0.42 to − 0.03 0.02 Heterogeneity (I2): 0.00

CI confidence interval.