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. 2021 Nov 11;12:6508. doi: 10.1038/s41467-021-26796-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — ai X-ray structure of the dimeric TPRs 11.5 construct¹⁴. aii Comparison of chain A to chain B demonstrates a 40° kink between chains. b X-ray structure of the catalytic domain of OGT appended to 4.5 TPRs, TPRs numbered¹³. c 5.3 Å cryo-EM map into which the cryo-EM model of the OGT dimer was fitted (d), orange and blue represent separate chains and their associated maps depicted at 40° rotations. e Chain A of the dimer assembly and the TPR units observed are numbered.