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. 2021 Nov 11;12:6508. doi: 10.1038/s41467-021-26796-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a The crystal structure of the 11.5 TPR construct with helices presented in expanded view depicted in darker shades. Enlarged view with residues subject to mutagenesis depicted. Dashed lines indicate hydrogen bonding. Purple and white denote separate chains, which form the dimer b SEC-MALLS trace demonstrating the multimeric state of OGT. Differential refractive index value depicted as a single continuous trace across the X-axis, while molecular weight estimates shown just for the region analysed. Source data are provided as a Source Data file.