Fig. 6.

In vivo antitumor efficacy of 17-DMAG-HMPB@sPP@HA on B16 xenograft tumor bearing mice. (a) Schematic diagram of the tumor model establishment and treatment of 17-DMAG-HMPB@sPP@HA on the B16 xenograft tumor bearing mice. (b) Photothermal images of mice under an 808 nm laser irradiation after different treatments. (c) Temperature change curves at the subcutaneous tumor site under laser irradiation. The body weight changes (d), tumor volume changes (e) and the final tumor weights (f) of C57BL/6 mice after different treatments. (g) Images of final tumor tissues collected from tumor-bearing mice. (h) Images of mice after the various treatments, wherein tumor growths were compared to the beginning of treatment. (n = 5, mean ± SD, *p < 0.05, **p < 0.01).