Table 5.
Patient use of healthcare utilization and associated costs in the 6 months pre- and post-erenumab stratified by persistence
| Pre-erenumab | Post-erenumab | |||||
|---|---|---|---|---|---|---|
| All (N = 4437) | Erenumab persistent (N = 1853) | Erenumab non-persistent (N = 2584) | All (N = 4437) | Erenumab persistent (N = 1853) | Erenumab non-persistent (N = 2584) | |
| Inpatient hospitalizations | ||||||
| Mean (SD) | 0.1 (0.3) | 0.1 (0.3) | 0.1 (0.3) | 0.1 (0.3) | 0.0 (0.2) | 0.1 (0.3) |
| 95% CI | (0.1, 0.1) | (0.0, 0.1) | (0.1, 0.1) | (0.0, 0.1) | (0.0, 0.1) | (0.1, 0.1) |
| Length of stay, days | ||||||
| Mean (SD) | 5.2 (3.9) | 4.6 (2.5) | 5.6 (4.5) | 5.2 (4.3) | 4.4 (3.2) | 5.5 (4.7) |
| 95% CI | (4.7, 5.7) | (4.0, 5.1) | (4.9, 6.3) | (4.6, 5.8) | (3.7, 5.2) | (4.7, 6.3) |
| Mean (SD) costs | $1680 ($9995) | $1403 ($8316) | $1879 ($11,040) | $1696 ($19,939) | $957 ($6515) | $2227 ($25,527) |
| ER visits | ||||||
| Mean (SD) | 0.5 (2.2) | 0.5 (2.9) | 0.4 (1.4) | 0.4 (1.4) | 0.4 (1.4) | 0.4 (1.4) |
| 95% CI | (0.4, 0.5) | (0.4, 0.6) | (0.4, 0.5) | (0.3, 0.4) | (0.3, 0.4) | (0.4, 0.5) |
| Mean (SD) costs | $657 ($3581) | $636 ($4227) | $673 ($3035) | $533 ($2401) | $500 ($2738) | $557 ($2127) |
| Outpatient office visits | ||||||
| Mean (SD) | 8.5 (7.9) | 8.2 (7.5) | 8.7 (8.2) | 8.0 (7.8) | 7.7 (7.2) | 8.3 (8.2) |
| 95% CI | (8.2, 8.7) | (7.9, 8.5) | (8.4, 9) | (7.8, 8.2) | (7.3, 8.0) | (8.0, 8.6) |
| Mean (SD) costs | $1143 ($1951) | $1128 ($2381) | $1154 ($1572) | $1049 ($1473) | $1024 ($1676) | $1067 ($1308) |
| Brain imaginga studies | ||||||
| Mean (SD) | 0.2 (0.5) | 0.2 (0.5) | 0.2 (0.5) | 0.1 (0.4) | 0.1 (0.4) | 0.1 (0.4) |
| 95% CI | (0.2, 0.2) | (0.1, 0.2) | (0.2, 0.2) | (0.1, 0.1) | (0.1, 0.1) | (0.1, 0.2) |
| Mean (SD) costs | $170 ($606) | $166 ($643) | $173 ($577) | $110 ($503) | $84 ($459) | $129 ($531) |
| Total associated costsb mean (SD) | $3651 ($11,736) | $3334 ($10,921) | $3879 ($12,285) | $3389 ($20,457) | $2564 ($7786) | $3980 ($25,969) |
a(CT + MRI + Nuclear Med + Angiography)
bTotal associated costs include inpatient, ER, office visits, and brain imaging studies