| Why carry out this study? |
| The literature lacks formally validated and reliable tools for the diagnosis of bBreakthrough cancer pain (BTcP). |
| The Italian Questionnaire for BTcP diagnosis (IQ-BTP) is an 11-item questionnaire aimed at detecting the presence of potential-BTcP and classifying it into three likelihood classes: high, intermediate, and low. |
| A multicenter, prospective, and observational study was designed to formally validate the IQ-BTP and to highlight its clinical usefulness. |
| What was learned from the study? |
| The IQ-BTP showed satisfactory psychometric and validity properties. |
| The IQ-BTP enabled potential-BTcP to be identified and differentiated into three likelihood classes with direct congruent therapeutic and epidemiological implications. |
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