Table 1.
Analysis of progression factors in de novo HGM patients after RT.
Feature | Progression | Non-progression | p-value | |
---|---|---|---|---|
Patients, n (%) | 19 (51.35) | 18 (48.65) | ||
Age, n (%) | ||||
<65 | 13 (68.42) | 14 (77.78) | 0.71 | |
≥65 | 6 (31.58) | 4 (22.22) | ||
Gender, n (%) | ||||
Male | 11 (57.89) | 12 (66.67) | 0.74 | |
Female | 8 (42.11) | 6 (33.33) | ||
Location, n (%) | ||||
Skull base | 3 (15.79) | 2 (11.11) | 1.00 | |
Non-skull base | 16 (84.21) | 16 (88.89) | ||
WHO grade, n (%) | ||||
2 | 16 (84.21) | 16 (88.89) | 1.00 | |
3 | 3 (15.79) | 2 (11.11) | ||
EOR, n (%) | ||||
GTR | 14 (73.68) | 1 (5.56) | <0.001** | |
STR | 5 (26.32) | 17 (94.44) | ||
TERT status, n (%) | ||||
TERT (+) | 8 (42.11) | 0 (0) | 0.003* | |
TERT (-) | 11 (57.89) | 18 (100) |
GTR, gross total resection; HGM, high-grade meningioma; RT, radiotherapy; STR, subtotal resection; EOR, extent of resection.
*p < 0.05 and **p < 0.001 considered statistically significant.