Table 6.

Indications on the selection of the most adequate NSAID according to the cardiovascular and gastrointestinal risk, in patients with high renal risk

High renal risk
CV risk	GI risk
	Low	High
Low	Diclofenac/other selective COX-2 inhibitors at the lowest effective level, for no longer than 7 to 10 days	Any NSAID
High	Any NSAID	Any NSAID
High + LDA	Any NSAID	Any NSAID

In italics, compounds indicated based on the available randomized controlled trials. Underlined, compounds contraindicated based on the available randomized controlled trials

GI gastrointestinal, COX-2 cyclooxygenase, NSAID non-steroidal anti-inflammatory drug, CV cardiovascular, LDA low-dose aspirin