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. 2021 Sep 4;10(2):1467–1479. doi: 10.1007/s40122-021-00310-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 2 — Structural equation modeling. Structural equation modeling (SEM) on the impact of neuropathic pain on disease activity and psychology. BASDAI and ASDAS-CRP were used as the disease activity index, and HAD-A and HAD-D were used as the psychological index. SEM was successfully established (probability level = 0.227; ratio of Chi-square to degree of freedom [CMIN/DF] = 1.413; comparative fit index [CFI] = 0.996; normed fit index [NFI] = 0.987; and root mean squared error of approximation [RMSEA] = 0.048). According to SEM, PDQ could alter the disease activity (β = 0.62, P < 0.001), and the disease activity could influence the psychological status (β = 0.42, P < 0.001)