Table 1.
Demographic and clinical characteristics of PUMCH patients.
| Patient ID | Sex | Age at dx of MAS (y) | Age at sx of PP (y) | Age at dx ofGH excess (y) | Café au lait | Polyostotic FD | CFFD | Height Z-score | Other endocrinopathies | Hearing or olfactory deficits | Visual Deficits |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | 6.3 | 5.0 | 6.3 | + | + | + | 3.3 | None | Unilateral hyposmia | Bilateral temporal hemianopia |
| 2 | M | 8.9 | 7.0 | 8.9 | + | + | + | 2.1 | None | Hyposmia | Unilateral visual field defect |
| 3 | F | 4.7 | 1.0 | 4.7 | + | + | + | 4.0 | None | None | None |
| 4 | F | 7.0 | 7.0 | 27 | − | + | + | -0.7 | None | None | Diplopia |
| 5 | F | 4.3 | 4.0 | 6.6 | − | + | + | 4.1 | None | CHL | None |
| 6 | M | 6.3 | 5.0 | 6.3 | + | + | + | 4.53 | None | CHL | Unilateral visual field defect |
| 7 | F | 2.1 | 1.0 | 6.4 | + | + | + | 1.9 | Hyperthyroidism | None | None |
CHL, conductive hearing loss; Dx, diagnosis; Sx, symptom and sign; FD, fibrous dysplasia; CFFD, craniofacial fibrous dysplasia; PP, precocious puberty. Height Z-score was recorded at the first visit.