Table 2.

Overview of receptors for HLA-G and their interactional role.

Receptors	Immune cell type	Interactional role
IL2	T cell	Inhibition of proliferation, cytolysis, chemotaxis and cytotoxicity; Inhibition of IFN-γ secretion of γδT cells Induction of Tregs and Th2-type cytokine; Induction of IL-10, IL-4 and TGF-β secretion
	B cell	Inhibition of proliferation, chemotaxis and Ig secretion
	NK cell	Inhibition of cytotoxicity and chemotaxis; Inhibition of MICA/NKG2D activation; Inhibition of IFN-γ secretion
	dendritic cell	Inhibition of maturation; Induction of tolerogenic DC and anergy and suppressor T cell; Induction of IL-10 and TGF-β secretion
	IL-10-differentiated DC	Induction of Tregs
	myeloid-derived suppressor cell	Induction of Tregs
	macrophage	M2 bias; Induction of IL-10, IL-4 and TGF-β secretion
IL4	dendritic cell	Inhibition of maturation; Induction of tolerogenic DC and anergy and suppressor T cell
	IL-10-differentiated DC	Induction of Tregs
	myeloid-derived suppressor cell	Induction of Tregs
	macrophage	M2 bias; Deviation of APC to tolerogenic phenotype
	Neutrophils	Inhibition of reactive oxygen species production and phagocytosis
KIR2DL4	NK cell	Induction of transcytosis, apoptosis and active Akt pathway; Induction of protective factors secretion; Induction of TNF-α, INF-γ, IL-10 and IL-1β secretion; Inhibition of killing targeted cell
CD8	CD8+T cell	Inhibition of proliferation, chemotaxis and cytotoxicity; Inhibition of IFN-γ secretion
CD160	Endothelial cell	Angionesis