Table 5.

Less abundant classically secreted proteins found in ERS CM.

Accession	Description	Max fold change
ESM1_HUMAN	Endothelial cell-specific molecule 1 – ESM1	15.4
PTX3_HUMAN	Pentraxin-related protein - PTX3	4.2
CO9_HUMAN	Complement component - C9	4.0
ISLR_HUMAN	Immunoglobulin superfamily containing leucine-rich repeat protein	3.5
ANXA6_HUMAN	Annexin A6 – ANXA6	3.2
SFRP2_HUMAN	Secreted frizzled-related protein 2 – SFRP2	2.4
LOXL3_HUMAN	Lysyl oxidase homolog 3 – LOXL3	2.4
PAI1_HUMAN	Plasminogen activator inhibitor 1 – SERPINE1	2.2
PGS1_HUMAN	Biglycan – BGN	2.2
ANXA5_HUMAN	Annexin A5 – ANXA5	2.2
GDN_HUMAN	Glia-derived nexin – SERPINE2	1.6
LTBP2_HUMAN	Latent-transforming growth factor beta-binding protein 2 – LTBP2	1.5