TABLE 3.
List of metabolites significantly different between Lactobacillus CFS belonging to high anti-Candida activity group and low anti-Candida activity group (p < 0.05) and concentrations, calculated as differences with respect to MRS medium [median value ± MAD (mmol/L)].
Metabolites | High-activity CFS | Low-activity CFS |
Amino acids and derivatives | ||
Glycine | −0.3130 ± 0.0406 | −0.1280 ± 0.0770 |
Histidine | 0.2398 ± 0.0091 | 0.0886 ± 0.0748 |
Isoleucine | 0.1051 ± 0.0188 | 0.2457 ± 0.0427 |
Methionine | 0.0747 ± 0.0113 | −0.3244 ± 0.1486 |
Proline | 0.0878 ± 0.0080 | 0.1261 ± 0.0143 |
Valine | 0.3559 ± 0.0342 | 0.5096 ± 0.0647 |
Sarcosine | 0.0570 ± 0.0155 | 0.5450 ± 0.1427 |
Organic acids | ||
Acetate | 4.6614 ± 0.5951 | −12.2848 ± 3.5317 |
Lactate | −0.0499 ± 0.0293 | 0.1147 ± 0.0749 |
Pyruvate | 0.1285 ± 0.0199 | 0.0311 ± 0.0244 |
Sugars | ||
Fructose | −3.0765 ± 0.0353 | −0.5228 ± 0.9609 |
Galactose | 0.0436 ± 0.0171 | 0.0169 ± 0.0102 |
Glucose | −83.9781 ± 0.0512 | −58.5522 ± 13.3528 |
Ribose | 0.0266 ± 0.0017 | 0.0609 ± 0.0340 |
myo-Inositol | −0.0588 ± 0.0197 | −0.1496 ± 0.0204 |
Others | ||
sn-Glycero-3-phosphocholine | 0.0284 ± 0.0051 | 0.0083 ± 0.0072 |
Orotate | 0.0059 ± 0.0015 | −0.0005 ± 0.0008 |
Uracil | −0.0167 ± 0.0064 | 0.0527 ± 0.0253 |