TABLE 2.
Common data element Links at FITBR for Preclinical Study of TBI and Anxiety.
CDE Group | No. Elements | Short Description | Key Reference/Example | Cdc.nlm.nih.gov.link |
Main Group* | 88 | General information about study, animal characteristics, injury* | #Table 1 (Smith et al., 2015), Table 1 (LaPlaca et al., 2021) | http://www.ncbi.nlm.nih.gov/pubmed/26058402 https://www.ncbi.nlm.nih.gov/pubmed/33297844 |
Animal Characteristics | 83 | Species, strain, age, genetics, sex, vendor | #Table 1 (Smith et al., 2015), Table 1 (LaPlaca et al., 2021) | http://www.ncbi.nlm.nih.gov/pubmed/26058402 https://www.ncbi.nlm.nih.gov/pubmed/33297844 |
TBI Model | ||||
CCI | 29 | Surgery and device descriptors, impactor type and settings, craniectomy | #Table 2 (Smith et al., 2015) | https://cde.nlm.nih.gov/formView?tinyId=7yeWOg_x |
FPI | 32 | Surgery and device descriptors, peak pressure and settings, craniectomy | #Table 2 (Smith et al., 2015) | https://cde.nlm.nih.gov/formView?tinyId=QsDZ8Ltd |
Blast | 66 | Device descriptors, driver gas, pressure descriptors, body exposure and orientation | #Table 1 (Rodriguez et al., 2018), #Table 2 (McCabe and Tucker, 2020) | https://www.ncbi.nlm.nih.gov/pubmed/29160141 https://cde.nlm.nih.gov/formView?tinyId=wn_HMj65 |
CHIMERA | 20 | Device descriptors, impact variables; linear/angular velocity and acceleration (g), head displacement | #Table 7 (McNamara et al., 2020) | http://www.ncbi.nlm.nih.gov/pubmed/32692987 |
Weight Drop | Surgery and device descriptors, weight drop height, mass | #Table 2 (Smith et al., 2015) | http://www.ncbi.nlm.nih.gov/pubmed/26058402 | |
Projectile Impact | Surgery and device descriptors, contact pressure | #Table 2 (Smith et al., 2015) | http://www.ncbi.nlm.nih.gov/pubmed/26058402 | |
Behavioral Readouts | ||||
Open Field Test | 69 | Behavioral measures, equipment descriptors, scoring/software, room environment, acclimation, injury elapsed time | https://cde.nlm.nih.gov/formView?tinyId=7JB1cozsN | |
EPM | 35 | https://cde.nlm.nih.gov/formView?tinyId=7JgyTujfoN | ||
EZM | 35 | https://cde.nlm.nih.gov/formView?tinyId=Xyz1KoMj4 | ||
Light-Dark Box | 10 | See Table 3 |
*Many of these features also appear in other Form Structures described below Main Group. #These publications are available as Open Access. https://cde.nlm.nih.gov/form/search?selectedOrg=NINDS&classification=Preclinical%20TBI.