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. 2021 Jul 14;9:15–28. doi: 10.1016/j.bioactmat.2021.07.009

Fig. 3.

Fig. 3

In vitro performance of amino acid-conjugated NPs in MCF7 cells and HUVEC cells. The uptake profiles of amino acid-conjugated NPs in MCF7 cells after incubation with different formulations for (A) 0.5 h and (B) 1 h. Scale bar = 50 μm. (C) Quantitative analysis of uptake normalized to free C6. C6@NPs group was selected as a control for comparison. (D) MTT assay in MCF7 cells. (E) HUVEC tube formation in Matrigel with various drug treatments (scale bar = 100 μm); (F) quantitative analysis; the untreated group was selected as a control for comparison. Data are presented as mean ± SD (n = 3). *, p < 0.05, **, p < 0.01, compared with the control group.