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Biodistribution of DiR@Trp-NPs in MCF7 tumor-bearing mice. (A) In vivo fluorescence images of MCF7 tumor-bearing mice at 2, 4, 8, and 12 h after i.v. injection of free DiR, DiR@NPs and DiR@Trp-NPs. (B) Fluorescence images of vital organs, collected at 12 h. (C) Quantitative analysis of the fluorescence signals in the tumor site at different time points. (D) Fluorescence ratio of each organ as percent of total fluorescence (all organs and tumor). Data are means ± SD (n = 3).
