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. 2021 Jul 14;9:15–28. doi: 10.1016/j.bioactmat.2021.07.009

Fig. 7.

Fig. 7

The in vivo anticancer efficacy and safety of LJ@Trp-NPs in MCF7 tumor-bearing mice. (A) Experimental design. (B) Tumor growth curves following treatment with saline, lapatinib (L), lapatinib + JPH203 (LJ), L@NP, LJ@NP and LJ@Trp-NP. (C) Photograph of tumors collected at day 18. (D) Tumor weight of MCF7 tumor-bearing mice in different groups at day 18. (E) Body weight of MCF7 tumor-bearing mice in different groups following treatments. Data are presented as means ± SD (n = 6). *, p < 0.05, **, p < 0.01, ***, p < 0.001, indicate statistical difference between groups. #, p < 0.05, ##, p < 0.01, indicate statistical difference compared to the control group.