The anti-metastasis effect of LJ@Trp-NPs in MCF7 tumor-bearing mice. Representative H&E staining of (A) liver sections and (B) lung sections from each group. Scale bar = 50 μm, (n = 3). (C) Representative images of lung metastasis in each group. The arrow represents pulmonary metastatic nodule. The number of (D) liver and (E) lung metastatic nodules after various treatments. Serum biochemical analysis of (F) AST, (G) ALT, (H) BUN, (I) creatinine after various treatments (n = 6). *, p < 0.05, **, p < 0.01, ***, p < 0.001, statistical difference between groups or compared to the control group.