FIGURE 3.

In situ vaccination inhibited local and distant tumors. (A) Treatment schema of the in situ vaccine. Kunming mice were implanted with H₂₂ hepatocellular carcinoma cells (2 × 10⁶) in both abdomen of mice on day 0, and received treatments on day 5, 7 and 9. Growth curves represent the average volumes of treated tumors (B) and untreated tumors (C). (n = 6). (d) Pictures of representative mice were taken on day 15. The tumor of each mouse was circled. (E‐L) Tumor growth curves of each group. (M) Survival curves. (n = 6). P‐value: *, P <.05; ***, P <.0001; n.s, not significant