FIGURE 1.

Screening of candidate compounds. 8305C cells were treated with either 10 μM each compound alone from SCADS* inhibitor kit or a combination of 10 μM lenvatinib and 10 μM compound. Cell viability was calculated using a cell viability assay after 48 h and shown as a scatter plot. The horizontal axis shows the cell viability following treatment with the compound alone, and the vertical axis shows the cell viability following treatment with the combined use of lenvatinib and a compound. The vertical dotted line represents 90% cell viability of the compound alone, and the horizontal dotted line represents the 50% cell viability of the combination of lenvatinib and a compound. The large dot represents a compound with less than 10% reduction in cell viability when treated alone and more than 50% reduction when treated in combination with lenvatinib. *Screening committee of anticancer drugs