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. 2021 Oct 29;12:752924. doi: 10.3389/fphys.2021.752924

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Copyright © 2021 Abboud, Cicha, Ericsson, Chapleau and Singh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Cross-fostering of SHR prevents the age dependent increase in CD161 + cells and (B) CD4 + CD161 + cells observed in self-fostered SHR as previously reported (Singh et al., 2017) (Blue line). (C) Comparison of infiltration of proinflammatory CD161 + immune cells in aortic tissue in self-fostered cross-fostered WKY and SHR. (D) Representative dot plot of CD161 + cells in thoracic aorta of cross-fostered WKY (x-WKY) and cross-fostered SHR (x-SHR). Asterisks denote statistically significant (^∗∗P < 0.0075), whereas n.s. denotes statistically not significant results by one-way ANOVA and Sidak’s post hoc test.