Table 5.
Secondary outcomes for fascial closure suture type by treatment group and wound classification stratum, in randomised patients who had abdominal surgery
|
Clean-contaminated stratum (n=3051) |
Contaminated or dirty stratum (n=2662) |
|||||
|---|---|---|---|---|---|---|
| Coated suture (n=1535) | Non-coated suture (n=1516) | Treatment effect (RR, 95% CI) | Coated suture (n=1328) | Non-coated suture (n=1334) | Treatment effect (RR, 95% CI) | |
| SSI at discharge | ||||||
| Yes | 52 (5·6%) | 105 (7·1%) | 0·79 (0·60–1·03) | 236 (20·2%) | 240 (20·9%) | 0·99 (0·85–1·15) |
| No | 1383 (94·4%) | 1368 (92·9%) | .. | 930 (79·8%) | 911 (79·1%) | .. |
| Missing | 70 | 43 | .. | 162 | 183 | .. |
| Reoperation for SSI within 30 days of surgery | ||||||
| Yes | 10 (0·7%) | 6 (0·4%) | 1·70 (0·63–4·58)* | 39 (3·3%) | 37 (3·2%) | 1·03 (0·67–1·58) |
| No | 1446 (99·3%) | 1454 (99·6%) | .. | 1129 (96·7%) | 1132 (96·8%) | .. |
| Missing | 79 | 56 | .. | 160 | 165 | .. |
| Mortality within 30 days of surgery | ||||||
| Yes | 35 (2·3%) | 33 (2·2%) | 1·06 (0·67–1·69) | 123 (9·5%) | 117 (9·1%) | 1·04 (0·82–1·32) |
| No | 1454 (97·7%) | 1462 (97·8%) | .. | 1166 (90·5%) | 1167 (90·9%) | .. |
| Missing | 46 | 21 | .. | 39 | 50 | .. |
| Unplanned wound opening within 30 days of surgery | ||||||
| Yes | 215 (14·7%) | 212 (14·5%) | 1·00 (0·85–1·17) | 286 (24·3%) | 263 (22·4%) | 1·12 (0·98–1·28) |
| No | 1246 (85·3%) | 1252 (85·5%) | .. | 892 (75·7%) | 913 (77·6%) | .. |
| Missing | 74 | 52 | .. | 150 | 158 | .. |
| Length of hospital stay for index admission (days) | ||||||
| Median (IQR) | 5·0 (4·0–7·0) | 5·0 (4·0–8·0) | 1·01 (0·94–1·09)† | 8·0 (5·0–12·0) | 8·0 (5·0–13·0) | 1·07 (0·99–1·16)† |
| Missing | 72 | 43 | .. | 162 | 184 | .. |
| Readmission within 30 days of surgery | ||||||
| Yes | 29 (2·0%) | 40 (2·7%) | 0·72 (0·45–1·15) | 52 (4·4%) | 61 (5·2%) | 0·85 (0·60–1·22) |
| No | 1427 (98·0%) | 1423 (97·3%) | .. | 1118 (95·6%) | 1109 (94·8%) | .. |
| Missing | 79 | 53 | .. | 158 | 164 | .. |
| Return to normal activities within 30 days of surgery | ||||||
| Yes‡ | 599 (41·1%) | 592 (40·4%) | 1·01 (0·94–1·08) | 353 (30·2%) | 360 (30·8%) | 1·01 (0·91–1·11) |
| No | 857 (58·9%) | 872 (59·6%) | .. | 816 (69·8%) | 810 (69·2%) | .. |
| Missing | 79 | 52 | .. | 159 | 164 | .. |
Data are number (%), unless otherwise indicated. Percentages presented ignore any missing data. RR=relative risk. SSI=surgical site infection.
*
Age removed from model as model did not converge due to multicollinearity.
†
Data are hazard ratio (95% CI).
‡
Yes=completely returned to normal activities.