Figure 5.

iBATx DIO mice treated with Bacteroides did not exhibit inhibition of body weight

(A) Body weight changes in the indicated groups. Resection of interscapular BAT or sham operation was performed on 6-week-old HFD-fed mice that were randomly divided into four groups, i.e., sham + vehicle (n = 9), sham + Bac (n = 9), iBATx + vehicle (n = 17), and iBATx + Bac (n = 17).

(B) 1-g oral glucose-tolerance test. n = 9 per group.

(C) Amount of food intake.

(D) Weights of iWAT and eWAT.

(E) Experimental design.

(F) Body weight changes in the indicated groups. n = 9 per group.

(G) Plasma BCAA and BCKA levels.

(H) Weights of the BAT, iWAT, and eWAT. Data are shown as mean ± SEM. Two-way repeated measures ANOVA (A, C, F) and two-tailed unpaired Student's t test (B, D, G, H). BAT, brown adipose tissue; Ile, isoleucine; KIC, ketoisocaproate; KIV, ketoisovalerate; KMV, ketoisoleucine; Leu, leucine; NS, not significant; Val, valine; WAT, white adipose tissue.