The effects of MPB-BA on macrophage polarization with or without laser irradiation. Representative immunofluorescence images for CCR-7 (a, green) and CD206 (b, green) in macrophages cultured with different materials, scale bar = 50 μm. Nucleus (blue); cytoskeleton (F-actin, red). Flow cytometry results of macrophages cultured with various materials for CCR-7 (c). Quantitative analyses of the flow cytometry results of CCR-7 (d). Flow cytometry results of macrophages cultured with various materials for CD206 (e). Quantitative analyses of the flow cytometry results of CD206 (f), n =3. Error bars indicated means ± standard deviations. ***P < 0.001, ****P < 0.0001; one-way analysis of variance (ANOVA) with Dunnett’s multiple comparisons test.