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. 2021 Nov 12;2021(11):CD007125. doi: 10.1002/14651858.CD007125.pub3
Study ID Setting Country; trial start Early surgery (< 48 hours) Anaesthesia Type of surgery Early mobilisation? Early supported discharge? Current treatment practice? Notes
Inpatient rehabilitation
Baroni 2019 Hospital Italy; 2012 No (31%) NR NR, 7 (3%) had conservative treatment NR No No Italy ‐ generally has longer time to surgery
Cameron 1993 Hospital Australia; 1989 Mean 1.8 days NR NR No (part of intervention) No (part of intervention) No Usual care not well described
Chong 2013 Hospital Singapore; 2004 NR NR Inconsistent data from 93% population.
bipolar hemiarthroplasty 20.5%; Moore's hemiarthroplasty 17%; dynamic hip screw 50%; others. NR ‐ unlikely
49% were not weight‐bearing on admission to rehabilitation No No (except for Singapore) Not enough information but high rate of non‐weight‐bearing
Fordham 1986 Hospital UK; 1984 No, 48% within 2 days, but 30% 5 days or over NR Mixed but some dated. Included 59 (55%) screws; 20 (18.5%) pin and plates; 16 (15%) cemented Hastings NR, unlikely No No Dated trial
Galvard 1995 Hospital Sweden; 1988 NR NR Cervical: 2 nails; trochanteric: sliding screw NR No, long hospital stays No Dated trial
Gilchrist 1988 Hospital UK; 1984 Yes (90%) 96% general NR NR NR Unlikely Dated trial but early surgery
Huusko 2002 Hospital Finland; 1994 Likely. Median 1 day NR NR No (part of intervention) Not really. Moved to rehabilitation or local hospital ward Unclear Dated trial but early surgery
Jette 1987 Hospital USA; 1984 NR NR In part but some old implants No ‐ 6 weeks for unstable fractures No No Dated trial
Kennie 1988 Hospital UK; before 1986 NR (but recommended in a later paper 1990) spinal 24%
general 76% 42% hemiarthroplasty
43% dynamic hip screw No (part of intervention) No No Dated trial
Marcantonio 2001 Hospital USA; before 1999 NR NR NR in full No (part of intervention) NR Unclear Focus on delirium ‐ hard to judge
Naglie 2002 Hospital Canada; 1993 Mean 1.35 days NR Pin + plate 60% hemiarthroplasty 30% other 10% No (part of intervention) No No Dated trial (surgery)
Prestmo 2015 Hospital Norway; 2008 Mean 29 hours Mostly spinal anaesthesia (after pre‐op femoral nerve block) 41% hemiarthroplasty; 18% screws; 33% bone plates and screws; others No (part of intervention) Yes for intervention group Unclear Intervention includes several aspects of current practice
Sanchez Ferrin 1999 Hospital Spain; 1996 NR NR Vague NR NR No Spain ‐ generally has longer time to surgery
Shyu 2008 Hospital Taiwan; 2001 NR NR 37% hemiarthroplasty; 63% internal fixation No (part of intervention) NR but policy to send home quickly No (except for Taiwan) Taiwan’s healthcare system differs from those in most Western countries, including underdevelopment of community‐based, long‐term‐care services.
Shyu 2013a Hospital Taiwan; 2005 No, but mean 2.2 days NR 38% arthroplasty; 62% internal fixation No (part of intervention) NR but policy to send home quickly No (except for Taiwan) Comment in Shyu 2008 is likely to apply
Stenvall 2007a Hospital Sweden; 2000 Mean 25 hours NR 2 hook‐pins 35%; bipolar hemiarthroplasty: 56%; dynamic hip screw: 8.5% for basocervical fractures Yes policy within 24 hours No Unclear Types of surgery more common in Sweden
Swanson 1998 Hospital Australia; 1994 60 (84.5%) had surgery within 48 hours (11 exceptions; reasons given)
(part of intervention)
Regional anaesthesia used (63.2% versus 42.4%); (part of intervention) internal fixation (65%) or hemiarthroplasty (35%) No (part of intervention) No (part of intervention) Unclear Intervention includes several aspects of current practice
Tseng 2019 Hospital and community (intervention group) Taiwan; 2010 NR NR 45.5% arthroplasty; 54.5% internal fixation No (part of intervention) NR but policy to send home quickly No (except for Taiwan) Comment in Shyu 2008 is likely to apply
Uy 2008 Hospital Australia; 2001 NR NR hemiarthroplasty for intracapsular fractures;
compression screw and plate for trochanteric fractures Likely (also part of intervention) Special group (part of intervention) Unclear All came from nursing care facilities and control group of early return reflects usual practice
Vidan 2005 Hospital Spain; 1997 No, mean 77.2 hours 96% regional anaesthesia Non‐specific internal fixation (60%), replacement (35%), other No ‐ rehabilitation started on average 9.3 days No No Spain ‐ generally has longer time to surgery
Watne 2014 Hospital Norway; 2009 Yes, median 26 and 24 hours 92% spinal anaesthesia 44% hemiarthroplasty
54% osteosynthesis
1 total hip replacement
not operated 3 (1%) Yes (policy) Partly (part of intervention too). Length of stay data indicated this applied generally Yes (see next box) Note that no mention of specific early discharge for nursing home patients
Ambulatory rehabilitation
Ashe 2019 Community
(outpatients and home)
Canada; 2011 NR NR NR NR NR Unsure No details to judge
Crotty 2003 Hospital and community (intervention group) Australia; 1998 NR NR Internal fixation 41%; replacement 59%; 1 total hip replacementa Yes, median 1 day to mobilise No (part of intervention) Unsure Intervention includes several aspects of current practice
Crotty 2019 Community (nursing home / care facility) Australia; 2012 Yes (88% within 24 hours) NR More intramedullary nail for extracapsular fractures (79%); very few total hip replacements for intracapsular fractures (2.3%)a NR but unlikely in context Early discharge as back to nursing home Yes (for these patients) Country‐ and circumstances‐dependent. All came from nursing care facilities
Karlsson 2016 Hospital and community (intervention group) Sweden; 2008 NR NR NR Yes (policy) Yes for intervention group Unclear
Ryan 2006 Community (at home) UK; 2000 NR NR NR NR No. Length of hospital stay was probably over a month on average Unclear Unlikely in terms of discharge timing
Singh 2012 Community (outpatients and home) Australia; 2003 NR NR NR NR NR Unclear No information on these
Ziden 2008 Hospital and community (intervention group: home) Sweden; 2004 NR NR NR Yes, policy: within 48 hours No: supported discharge was an aim of one intervention but no indication of early Unclear Insufficient evidence to judge