Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The role of the catechol-O-methyltransferase (COMT) enzyme in norepinephrine inactivation. Based on this pathway, we suggest that impaired function of the COMT enzyme can lead to increased levels of norepinephrine. This pathway is further dependent on adequate levels of cofactors including vitamins B6, B9 and B12. *Low levels of product. SAM, S-adenosyl-L-methionine; SAH, S-adenosyl-L-homocysteine.
