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. Author manuscript; available in PMC: 2022 Jun 15.
Published in final edited form as: Biochemistry. 2021 Jun 3;60(23):1797–1807. doi: 10.1021/acs.biochem.1c00130

Figure 4:

Figure 4:

Mutational signature profile of SBS9 (hPol η) in reference human genome version GRCh37, using the conventional 96-mutation type classification. Data obtained through the Catalogue of Somatic Mutations in Cancer (COSMIC).51 Substitution mutation frequencies are presented as respective proportions of mutations of each trinucleotide signature based on the actual frequency of each trinucleotide sequence found in the genome version GRCh37. C to A transversions appear in blue (left panel), C to G transversions appear in orange (middle panel), and C to T transitions appear in green (right panel).