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. 2021 Oct 30;26(21):6583. doi: 10.3390/molecules26216583

Figure 4.

Figure 4

The superimposed docking poses of compounds AMC3 (light-blue) [25], AMC4 (magenta), and 14a (light-green) in the FPR1 binding site. The heterocyclic fragments of molecules AMC3, AMC4, and 14a are oriented in a similar fashion with meta-substituted benzene rings of compounds AMC3 and 14a and the ethoxy carbonyl group of AMC4 occupying the same area of space within the receptor cavity (Panel A); AMC3 (light-blue) [25] and 14c (yellow) docked in FPR1 with different orientations of N-phenylacetamido and phenylpyridinone moieties. (Panel B). Residues within 4 Å from AMC3 pose are visible.