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. 2021 Oct 28;7(4):e19812. doi: 10.2196/19812

Table 2.

Age, gender, and diseases with AUROC loss greater than 0.01% or OR greater than 4 or less than 0.3.

Characteristic AUROCa loss (%) (95% CI) ORb (95% CI) Patient number Age- and gender-matched OR (95% CI)

Age > 50 years 0.57 (0.6-0.54) 4.26 (4.0-4.49) 24,074 (50.2)c N/Ad

Male 0.39 (0.42-0.36) 1.97 (1.88-2.06) 24,671 (51.4)c N/A
ICD-9e (description)

571 (chronic liver disease and cirrhosis) 2.52 (2.35-2.62) 14.63 (13.75-15.58) 5753 11.08 (10.5-11.7)

070 (viral hepatitis) 0.67 (0.58-0.77) 11.36 (10.48-12.32) 3023 8.98 (8.4-9.6)

533 (peptic ulcer) 0.41 (0.69-0.13) 3.46 (3.22-3.72) 3446 2.92 (2.7-3.1)

456 (varicose veins of other sites) <0.01 22.47 (15.89-31.78) 246 14.31 (11.3-18.1)

573 (other disorders of liver) <0.01 5.34 (4.54-6.27) 611 3.93 (3.5-4.4)

794 (nonspecific abnormal results of function studies) <0.01 4.48 (3.59-5.6) 313 3.03 (2.6-3.6)

574 (cholelithiasis) <0.01 4.36 (3.75-5.06) 700 3.9 (3.4-4.4)

V76 (screening for malignant neoplasms) 0.78 (1.2-0.36) 0.42 (0.36-0.48) 2445 0.42 (0.4-0.5)

626 (disorders of menstruation and other abnormal bleeding from female genital tract) 0.14 (0.31-0.01) 0.3 (0.27-0.35) 3352 0.66 (0.6-0.7)

625 (pain and other symptoms associated with female genital organs) 0.16 (0.33-0.01) 0.25 (0.18-0.35) 674 0.57 (0.4-0.7)

V22 (normal pregnancy) <0.01 0.16 (0.12-0.22) 1180 0.44 (0.3-0.6)

aAUROC: area under the receiver operating curve.

bOR: odds ratio.

cThese data are presented as numbers and percentages.

dN/A: not applicable.

eICD-9: International Classification of Disease, Ninth Revision.