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. Author manuscript; available in PMC: 2021 Nov 12.
Published in final edited form as: Med Phys. 2021 Mar 2;48(4):1616–1623. doi: 10.1002/mp.14750

TABLE I.

Quantitative metrics obtained from projection images of a virtual patient with and without pleural invasion.

Oblique view
PA view
Invasion (+)
(n = 6)
Invasion (−)
(n = 12)
P-value Invasion (+)
(n = 6)
Invasion (−)
(n = 12)
P-value
(i) Ratio of the maximum displacement (D1/D2) 1.16 ± 0.25 3.48 ± 3.46 <0.01 1.19 ± 0.29 4.73 ± 4.10 <0.01
(ii) Cross-correlation coefficient (r) 0.92 ± 0.07 0.82 ± 0.12 <0.01 0.91 ± 0.03 0.75 ± 0.10 <0.01
(iii) Ratio of the total moved distances (T1/T2) 1.16 ± 0.25 3.51 ± 3.44 <0.01 1.19 ± 0.29 4.85 ± 4.26 <0.01
(iv) Cosine similarity between inspiratory andexpiratory vectors 0.99 ± 0.02 0.96 ± 0.05 <0.01 1.00 ± 0.00 0.97 ± 0.04 <0.05
(v) Cosine similarity between vectors of the cancer and the reference 0.98 ± 0.03 0.87 ± 0.15 <0.05 0.98 ± 0.03 0.88 ± 0.14 <0.05

Abbreviation: PA, posteroanterior.