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. 2021 Nov 9;9(2):e002570. doi: 10.1136/bmjdrc-2021-002570

Table 2.

Final ‘top-10’ research questions for the whole sample after Round 3 (n=69) comparing the rank in consumer or health professional subgroups

Overall sample rank Consumer rank Health professional rank Research question DFD category UKCRC HRCS category Final score
1 2 What are the health and cost benefits of providing government-funded, multidisciplinary high-risk foot services for optimal management of people with diabetes-related foot disease compared with usual care? Economics Health and social care services research 452
2 4 What are the most effective treatment options for pain associated with diabetes-related peripheral neuropathy? Peripheral neuropathy Management of diseases and conditions 431
3 4 What are the most effective educational programs to improve self-care practices to prevent foot disease in people with diabetes? Education Management of diseases and conditions 430
4 3 What are the long-term outcomes (wound recurrence, osteomyelitis recurrence) of osteomyelitis in people with diabetes, when treated conservatively/medically rather than surgically? Infection Management of diseases and conditions 413
5 1 Can established peripheral neuropathy be reversed, and if so how? Peripheral neuropathy Etiology 410
6 5 Is there a cost benefit of implementing a program to prevent diabetes-related foot ulcers in high-risk populations compared with the cost of treating diabetes-related foot ulcers? Economics Health and social care services research 381
7 What smart technology can be integrated into the care of people with diabetes-related foot ulcers that will help improve healing time? Technology Evaluation of treatments and therapeutic interventions 332
8 8 Is exercise beneficial in reducing the risk of diabetes-related foot complication? Exercise Evaluation of treatments and therapeutic interventions 327
9 What is the effectiveness of diet supplementation with micronutrients such as vitamins, protein, minerals and amino acids in improving healing rates in people with diabetes-related foot disease or ulcers? Nutrition Evaluation of treatments and therapeutic interventions 322
10 Is exercise safe for people with diabetes-related foot complications? Exercise Evaluation of treatments and therapeutic interventions 297

DFD, diabetes-related foot disease; UKCRC HRCS, UK Clinical Research Collaboration Health Research Classification System.