Table 1.
Compounds | MAO-A % Inhibition | MAO-B % Inhibition | ||
---|---|---|---|---|
10−3 M | 10−4 M | 10−3 M | 10−4 M | |
2a | 34.128 ± 0.927 | 22.314 ± 0.824 | 74.159 ± 1.412 | 46.356 ± 0.997 |
2b | 32.951 ± 0.955 | 28.357 ± 0.899 | 91.625 ± 1.652 | 87.357 ± 1.388 |
2c | 30.357 ± 0.902 | 26.735 ± 0.820 | 76.345 ± 1.623 | 43.451 ± 0.728 |
2d | 37.518 ± 0.897 | 20.856 ± 0.834 | 82.624 ± 1.318 | 41.052 ± 0.956 |
2e | 36.735 ± 0.910 | 23.402 ± 0.832 | 85.486 ± 1.528 | 40.828 ± 0.827 |
2f | 31.057 ± 0.994 | 24.174 ± 0.711 | 82.366 ± 1.332 | 47.398 ± 0.930 |
2g | 38.935 ± 0.854 | 28.692 ± 0.803 | 78.951 ± 1.702 | 44.774 ± 0.758 |
2h | 36.751 ± 0.741 | 21.873 ± 0.750 | 90.412 ± 1.602 | 84.362 ± 1.325 |
2i | 35.654 ± 0.863 | 29.162 ± 0.816 | 84.654 ± 1.628 | 46.035 ± 0.931 |
2j | 33.667 ± 0.729 | 23.041 ± 0.863 | 82.923 ± 1.621 | 42.957 ± 0.965 |
2k | 31.065 ± 0.911 | 27.859 ± 0.815 | 80.451 ± 1.475 | 46.651 ± 0.899 |
2l | 36.741 ± 0.966 | 24.389 ± 0.721 | 83.642 ± 1.597 | 42.249 ± 0.763 |
Clorgiline | 99.411 ± 1.955 | 98.257 ± 1.824 | - | - |
Selegiline | – | – | 99.387 ± 1.385 | 95.629 ± 1.456 |