Table 5.
Hydrogen bond in catechin–MurA and positive controls.
| Residues Binding at Ligand-Protein Complex | ||||
|---|---|---|---|---|
| Ligand | MurA | GBAP | Gelatinase | Serine Protease |
| Catechin | Ser162A, Gly164A, Asp305A, Ala297A | Arg15A, Ser33A, Val16A | His332A, Tyr343A, Glu329A, Asn298A | Asn145A, Asn262A, Asn268A, Leu212A |
| Fosfomycin | Arg120A, Asn23A, Arg371A, Asp305A | Arg28A, Gln31A, Lys26A | Arg384A, Glu329A, Asn298A, His419A | Asn214A, Asp147A |
| Ambuic acid | Lys22A, Arg91A, Arg120A | Ile36A | Arg384A, Glu352A | Asn99A, Ala146A, Ser143A, Asn214A, Asp147A |
| Quercetin | Ser12A, Gly164A, Glu188A, Phe328A | Glu45A, Gln43A, Trp40A | Asn298A, His332A, Glu336A, Tyr343A, Glu329A | Asn145A, Asn262A, Asn268A, Glu213A |
| Taxifolin | Ser162A, Gly164A, Asp305A, Asn23A, Arg397A, Asp49A, Lys22A | Asn35A, Arg15A, Ser33A, Gln31A | Asn351A, His332A, Asn298A, Glu329A, Trp301A | Arg46A, Ser83A, His195A |
Quercetin, fosfomycin, ambuic acid, and taxifolin were used as positive controls.