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. 2021 Nov 3;26(21):6661. doi: 10.3390/molecules26216661

Table 1.

List of the studied miRNAs and their functions.

MicroRNAs Biological Activity Reference
142 targets ESR1, reduces cell viability, induces apoptosis and decreases colony formation [72]
203a is overexpressed in breast cancer and can influence ERα signalling by targeting ADCY5, IGF1, etc. [73]
219b downregulates ERα [74]
520a targets NF-κB and TGF-β signalling pathways; targets ESR1, inhibits CCND1 mRNA and cyclin D1 protein levels [75,76]
874 targets ESR1, CDK9 [77]
181a downregulates ERα; induces AKT signalling [74,78]