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Time-dependent curve of cumulative amount permeated/area (A), permeation flux (µg/cm2/h) (B), and skin retention (µg/cm2) (C) of different diflunisal-loaded medical substances. SLN dispersion—solid lipid nanoparticles dispersion; SLN gel—solid lipid nanoparticles gel; C. cream—conventional oil/water (o/w) cream; CMC dispersion—aqueous diflunisal dispersion in 0.5% solution of sodium carboxymethyl cellulose (CMC). Reproduced from [25], with permission from Taylor & Francis, 2021.
