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(a) Accumulative amount of diflunisal permeated through rat skin from pure diflunisal dispersed in saline solution (■) and aqueous solution of a drug–dendrimer complex (●); (b) diflunisal concentration in animal plasma after treatment of pure diflunisal (●) and diflunisal–dendrimer complexes (◇). Reproduced from [72], with permission from Elsevier, 2021.
