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. Author manuscript; available in PMC: 2022 Sep 14.
Published in final edited form as: Mol Genet Metab. 2021 Sep 14;134(1-2):156–163. doi: 10.1016/j.ymgme.2021.09.002

Figure 7. Functional testing of skeletal muscle Acad9−/− mice.

Figure 7.

A. Kaplan-Meier-like curve measuring fall score of Acad9 deficient skeletal muscle-specific mice. Average of fall scores over a period of 180 seconds. While all normal mice were able to last the full three minutes, All mutants had received a final fall score of zero by 78 seconds. B. Blood L-lactate levels in skeletal-muscle specific Acad9 deficient mice measured before and after a hanging wire test. Muscle specific ACAD9 deficient mice have an increased resting L-Lactate levels compared to wild type littermates (blue), which increases more than wild type following exercise (orange; the hanging wire test). *p-value = 0.002, **p-value = 0.004. C. Blood glucose Levels in skeletal-muscle specific Acad9 deficient mice measured before and after a hanging wire test. Muscle specific Acad9 deficient mice do not have a significant difference of resting glucose levels or after exercise (orange) compared to wild type littermates (blue).