Table 1.

Histological data of the CDAA murine model

Variable	32 weeks				66 weeks
	CSAA		CDAA		CSAA		CDAA
	WT	Ripk3−/−	WT	Ripk3−/−	WT	Ripk3−/−	WT	Ripk3−/−
Steatosis (0–3)	0±0	1.7±0.§	3±0*	3±0*	1.3±0.7	3±0§	2.8±0.3§	3±0§
Inflammation (0–3)	0±0	0.3±0.3	2±0*	1±0.3§†	0±0	0±0	2.3±0.5*	0.8±0.3†
Ballooning (0–2)	0±0	0±0	1±0*	1±0*	0±0	0.3±0.3	1±0*	1±0*
NAS (0–8)	0±0	2±0.6	6±0*	5.3±0.3*	1.3±0.7	3.3±0.3	6.5±0.4*	4.7±0.3*†
Fibrosis (0–4)	0±0	0±0	1±0*	1±0*	0±0	0.3±0.3	2±0*	1±0*†

Values are mean±SEM of four individual mice.

^§P<0.05 from CSAA diet WT mice at respective time-point.

*P<0.01 from CSAA diet WT mice at respective time-point.

†P<0.05 from CDAA diet WT mice at respective time-point.

CDAA, choline-deficient L-amino acid; CSAA, choline-sufficient L-amino acid; NAS, NAFLD activity score; WT, wild-type.