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. 2021 Nov 6;26(21):6725. doi: 10.3390/molecules26216725

Table 1.

Statistically significant sialolith proteins (p-value < 0.05) qualified based on quantitative analysis as candidates for biomarkers of the formation of salivary glands.

Sialolith 2 Sialolith 3 Sialolith 4 Sialolith 5
Protein ID Group p-Value Fold Change Log (Fold Change) p-Value Fold Change Log (Fold Change) p-Value Fold Change Log (Fold Change) p-Value Fold Change Log (Fold Change)
P63261 Actin. cytoplasmic 2 0.0000556 7.284207094 0.862382285
P59998 Actin-related protein 2/3 complex subunit 4 0.04393 8.260782456 0.917021185
P02768 Albumin 0.03581 1.541531139 0.187952302
P04745 Alpha-amylase 1 0.00116 0.418105336 −0.378714289 0.00073 0.212342882 −0.672962293 0.0000533 6.938583149 0.841270797 0.00174 0.276827038 −0.557791494
P01008 Antithrombin-III 0.03109 1.7503964 0.243136411 0.03258 2.069788471 0.315925964
P08311 Cathepsin G 0.03194 0.215401717 −0.66675084
P28325 Cystatin-D 0.00014 12.34453279 1.091474658
P01036 Cystatin-S 0.04307 3.873435826 0.588096365
P01037 Cystatin-SN 0.04697 2.411624112 0.382309617
P12724 Eosinophil cationic protein 0.02326 0.727721066 −0.138035053 0.0031 0.486055211 −0.313314396 0.0000154 4.412958749 0.644729868
P11678 Eosinophil peroxidase 0.04349 0.419790017 −0.376967894
P00738 Haptoglobin 0.02436 0.454821305 −0.3421592 0.00809 0.228983086 −0.640196596 0.00067 3.059357569 0.485630239
P69905 Hemoglobin subunit alpha 0.01515 0.30617954 −0.514023834 0.00391 0.015164453 −1.819173248 0.01928 1.689412748 0.227735767
P68871 Hemoglobin subunit beta 0.00904 0.542480283 −0.265616042 0.0000434 0.132372198 −0.878203219
P02042 Hemoglobin subunit delta 0.02124 2.668392602 0.426249728
Q99880 Histone H2B type 1-L 0.04376 0.382441371 −0.417435133
P62805 Histone H4 0.00074 0.615579981 −0.210715512 0.00077 0.569335782 −0.24463152 0.00023 3.057790931 0.485407788 0.03587 1.337430686 0.126271284
P02788 Lactotransferrin 0.03229 2.969429146 0.472672967 0.02921 0.215013951 −0.66753336
P30740 Leukocyte elastase inhibitor 0.00072 0.295559993 −0.529354352 0.00044 0.270358218 −0.568060425 0.0000901 8.758657111 0.942437525 0.0134 0.44069474 −0.355862133
P08493 Matrix Gla protein 0.00909 5.121921883 0.709432951
P98088 Mucin-5AC 0.02361 0.35644789 −0.448003952 0.0198 0.357020126 −0.447307301 0.00386 3.117583194 0.493818052
Q8TAX7 Mucin-7 0.00921 1.683950908 0.226329426 0.01667 0.435705277 −0.36080718 0.0271 0.517439675 −0.286140275
P24158 Myeloblastin 0.04279 0.440744162 −0.355813431 0.012 0.300535469 −0.522104266 0.00643 4.525451976 0.65566196 0.02779 1.55929247 0.192927582
P05164 Myeloperoxidase 0.00425 6.591029535 0.818953258
P80188 Neutrophil gelatinase-associated lipocalin 0.00821 8.288015407 0.91845055
O75594 Peptidoglycan recognition protein 1 0.00758 0.184102407 −0.734940533 0.01342 1.71067952 0.233168656
P12273 Prolactin-inducible protein 0.04007 3.075452718 0.487909055
Q6MZM9 Proline-rich protein 27 0.04956 5.728810271 0.758064439 0.01618 0.473683666 −0.324511591
P80511 Protein S100-A12 0.04541 0.426860545 −0.369713985 0.04279 1.814077348 0.2586558
P06702 Protein S100-A9 0.00073 2.087914099 0.319712627
P02808 Statherin 0.02952 4.175986159 0.620759051
P02814 Submaxillary gland androgen-regulated protein 3B 0.00181 2.030083123 0.307513821 0.00293 0.135815988 −0.867049102 0.0031 0.104953618 −0.979002587
P25311 Zinc-alpha-2-glycoprotein 0.03592 3.065769997 0.48653957
Q96DA0 Zymogen granule protein 16 homolog B 0.02283 0.793156904 −0.100640891 0.04406 0.747544585 −0.1263629 0.00000717 3.008601253 0.478364632